A new species of Meliosma (Sabiaceae), M. longepedicellata, from southeastern Ecuador, in the Amotape-Huancabamba zone, is described and illustrated. The new species mainly differs from the Venezuelan M. tachirensis in having inflorescences with longer pedicels (3.0–6.0 vs. 0.5–3.0 mm), flower buds globose before anthesis (vs. flower buds oblong), shorter outer petals (2.0–2.5 vs. 3.0–3.5 mm), and staminodes of subsquare shape (vs. staminodes lanceolate). Relationships with other morphologically related species are also discussed.