Draba beltranii and D. werffii (Brassicaceae) are described from the Peruvian departments of Lima and Arequipa, respectively. Draba beltranii differs from the related D. cuzcoensis and D. soratensis by having more ovules per ovary (30–34 vs. 14–26) and longer fruits and pedicels, and from the former by the bracteate raceme and from the latter by the yellow instead of white flowers. Draba werffii differs from all South American species by a combination of small (2.5–3.0 × 0.7–1.0 mm), blue or purple flowers, scapose habit, and ebracteate racemes.