The cloud forests comprise high levels of species richness and endemism, and are the most threatened habitat in Mexico. They are listed as priority regions for conservation nationwide. Here, we estimated species richness and relative abundance of birds and mammals using camera-traps in a cloud forest located in a biodiversity hotspot of Mexico. From December 2013 to December 2014, we sampled 538 independent records from 27 species, including 11 species listed with some level of threat. Expected species richness, using first-order Jackknife estimator, was 37.08 species DE ± 2.86. We reported the greatest number of birds and mammals observed in cloud forests using camera-traps, and a high relative abundance index for some species. We found a significant difference between species composition observed in our study and other studies using camera-traps in Mexico. We observed a similar species composition in a nearby tropical rainforest habitat, suggesting that the recorded species are not restricted to cloud forests and move between different habitats. This highlights the importance of this region as a connector with “Los Chimalapas,” the largest and northernmost rain forest patch in Mexico.