If the life sciences are to have much to say about politics, there needs to be a universal element to political orientations. In this essay, I argue that the recent prominence of nativist, law-and-order, populist politicians reveals the nature of this universal element. All social units have to address bedrock dilemmas about how to deal with norm violators and how welcoming to be to outsiders as well as to proponents of new lifestyles. Might differences on these core dilemmas be the universal element of political life? Using the followers of one of the most prominent examples of a nativist political leader—Donald Trump—as an example, I present data showing that Trump's most earnest followers are different from others—even those who share their general ideological leanings—not on traditional economic or social issues, but rather on the group-based security issues that grow out of the bedrock dilemmas of social life.