Currently there is limited information on blood-parasite distribution and diversity in wildlife in North America, particularly for some groups such as reptiles, despite their potential impact on their hosts. Snakes and small mammals were surveyed in the Huyck Preserve, NY, during September 2013. No snakes were infected, but a Peromyscus leucopus (White-footed Mouse) was positive. Similarity of the 18S rRNA gene with data from Gen-Bank indicates that Hepatozoon spp. from snakes and small mammals are related, further highlighting a possible role for trophic transmission.