The pancreas of 231 dasyurid marsupials was examined. Focal interstitial pancreatitis was found in 22 animals, an exocrine adenoma in an Antechinus macdonnellensis and an islet cell adenoma in an Antechinus apicalis. Glycogenic vacuolation of islet cells found in one Antechinus sp. nov. and one Antechinus rosamondae is taken as evidence for spontaneous diabetes mellitus.