A new Cotyledon is described from the Goukou River near Stilbaai in the Western Cape. Cotyledon lutea is a distinct, semi-scandent plant from the thicket vegetation of the Goukou Rivier. It differs from other Cotyledon species by its yellow flowers on long pedicels bearing transversely oblong emarginate squamae. At 3 mm in diameter, these are the largest recorded for the genus Cotyledon.