Thirteen herbicide tankmixes were evaluated during 2013–2015 for control of glyphosate-resistant (GR) Canada fleabane in soybean. Glyphosate saflufenacil s-metolachlor/metribuzin, glyphosate amitrole, and glyphosate metribuzin were the most efficacious, controlling 86%–92% of GR Canada fleabane, reducing density by 98%–99% and aboveground biomass by 96%–97%.