AASRA: an anchor alignment-based small RNA annotation pipeline
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Chong Tang; Yeming Xie; Mei Guo; Wei Yan

doi:10.1093/biolre/ioab062

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31 March 2021 AASRA: an anchor alignment-based small RNA annotation pipeline

Chong Tang, Yeming Xie, Mei Guo, Wei Yan

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Biology of Reproduction, 105(1):267-277 (2021). https://doi.org/10.1093/biolre/ioab062

Abstract

Small noncoding RNAs deep sequencing (sncRNA-Seq) has become a routine for sncRNA detection and quantification. However, the software packages currently available for sncRNA annotation can neither recognize sncRNA variants in the sequencing reads, nor annotate all known sncRNA simultaneously. Here, we report a novel anchor alignment-based small RNA annotation (AASRA) software package ( https://github.com/biogramming/AASRA). AASRA represents an all-in-one sncRNA annotation pipeline, which allows for high-speed, simultaneous annotation of all known sncRNA species with the capability to distinguish mature from precursor microRNAs, and to identify novel sncRNA variants in the sncRNA-Seq sequencing reads.

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Chong Tang, Yeming Xie, Mei Guo, and Wei Yan "AASRA: an anchor alignment-based small RNA annotation pipeline," Biology of Reproduction 105(1), 267-277, (31 March 2021). https://doi.org/10.1093/biolre/ioab062

Received: 10 December 2020; Accepted: 29 March 2021; Published: 31 March 2021

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